Lessons from human T-lymphotropic virus testing

Incidence of Human T-Lymphotropic Virus Type 1 (HTLV-1) among Blood Donors from Ilam, Iran

Human T-cell Lymphotropic Virus

Retroviruses can be classified according to the morphology of their virion core or according to sequence homologies that become evident after phylogenetic analyses. Human T-lymphotropic virus type 1 (HTLV-1) is a member of the deltatype retrovirus group, other members of which include HTLV types 2, 3 and 4, bovine leukaemia virus (BLV), and simian T-cell leukaemia virus (STLV) types 1, 2 and 3 ...

Human T-cell lymphotropic virus-type I.

HTLV-I is a retrovirus now identified as the etiologic agent of two diverse disease processes: ATLL, an aggressive T-cell malignancy; and TSP/HAM, a chronic progressive myelopathy. Transmission can occur horizontally through blood transfusions, IV drug abuse and sexual intercourse. Vertical transmission may also occur. Available diagnostic modalities are serologic in nature and include the EIA ...

Study of the Association Between Human T-cell Lymphotropic Virus Type I Infection and Lichen Planus

Infection of human T lymphotropic virus-I-specific immune T cell clones by human T lymphotropic virus-I.

Human T lymphotropic virus-I (HTLV-I)-specific T cell lines were established and cloned. K5, an OKT8+ clone bearing multiple proviral integration sites, retained its HTLV-I-specific cytotoxicity and a normal dependence on interleukin 2 (IL-2), indicating that there is a finite number of transforming integration sites. R2, an OKT4+ HTLV-I-infected clone, initially mounted a proliferative respons...